Synthesis of 1,2-Dihydro-Substituted Aniline Analogues Involving N-Phenyl-3-aza-Cope Rearrangement Using a Metal-Free Catalytic Approach
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چکیده
منابع مشابه
A Theoretical Investigation of Kinetics and Mechanism of Aza-Cope Rearrangement
A theoretical study of the kinetic and mechanism of 3-aug-Cope rearrangement in gas phase was performed usingDET methods at B3LYP levels of theory with 6-3114iG(d,p) bass set at 298.I5K. Equilibrium moleculargeometries and harmonic vibrational frequencies of the reactant, transition state Did product were calculated. Then,rate constant and activation thermodynamics parameters were calculated an...
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BACKGROUND The nature of the heteroatom substitution in the nitrogen of a 3-aza-Cope system is explored. RESULTS While N-propargyl isoxazolin-5-ones suffer 3-aza-Cope rearrangements at 60°C, the corresponding N-propargyl pyrazol-5-ones need a higher temperature of 180°C for the equivalent reaction. When the propargyl group is substituted by an allyl group, the temperature of the rearrangement...
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ژورنال
عنوان ژورنال: Journal of Chemistry
سال: 2020
ISSN: 2090-9063,2090-9071
DOI: 10.1155/2020/9139648